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A machine learning case–control classifier for schizophrenia based on DNA methylation in blood

Epigenetic dysregulation is thought to contribute to the etiology of schizophrenia (SZ), but the cell type-specificity of DNA methylation makes population-based epigenetic studies of SZ challenging. To train an SZ case–control classifier based on DNA methylation in blood, therefore, we focused on hu...

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Detalles Bibliográficos
Autores principales: Gunasekara, Chathura J., Hannon, Eilis, MacKay, Harry, Coarfa, Cristian, McQuillin, Andrew, Clair, David St., Mill, Jonathan, Waterland, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329061/
https://www.ncbi.nlm.nih.gov/pubmed/34341337
http://dx.doi.org/10.1038/s41398-021-01496-3