Cargando…
A machine learning case–control classifier for schizophrenia based on DNA methylation in blood
Epigenetic dysregulation is thought to contribute to the etiology of schizophrenia (SZ), but the cell type-specificity of DNA methylation makes population-based epigenetic studies of SZ challenging. To train an SZ case–control classifier based on DNA methylation in blood, therefore, we focused on hu...
Autores principales: | Gunasekara, Chathura J., Hannon, Eilis, MacKay, Harry, Coarfa, Cristian, McQuillin, Andrew, Clair, David St., Mill, Jonathan, Waterland, Robert A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329061/ https://www.ncbi.nlm.nih.gov/pubmed/34341337 http://dx.doi.org/10.1038/s41398-021-01496-3 |
Ejemplares similares
-
Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data
por: Scott, C. Anthony, et al.
Publicado: (2020) -
Sex-specific epigenetic development in the mouse hypothalamic arcuate nucleus pinpoints human genomic regions associated with body mass index
por: MacKay, Harry, et al.
Publicado: (2022) -
Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control
por: Gunasekara, Chathura J., et al.
Publicado: (2023) -
An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation
por: Hannon, Eilis, et al.
Publicado: (2016) -
Methylation age acceleration does not predict mortality in schizophrenia
por: Kowalec, Kaarina, et al.
Publicado: (2019)