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The role of epigenetic modifications, long-range contacts, enhancers and topologically associating domains in the regulation of glioma grade-specific genes

Genome-wide studies have uncovered specific genetic alterations, transcriptomic patterns and epigenetic profiles associated with different glioma types. We have recently created a unique atlas encompassing genome-wide profiles of open chromatin, histone H3K27ac and H3Kme3 modifications, DNA methylat...

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Detalles Bibliográficos
Autores principales: Grabowicz, Ilona E., Wilczyński, Bartek, Kamińska, Bożena, Roura, Adria-Jaume, Wojtaś, Bartosz, Dąbrowski, Michał J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329071/
https://www.ncbi.nlm.nih.gov/pubmed/34341417
http://dx.doi.org/10.1038/s41598-021-95009-3