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USP42 drives nuclear speckle mRNA splicing via directing dynamic phase separation to promote tumorigenesis
Liquid–liquid phase separation is considered a generic approach to organize membrane-less compartments, enabling the dynamic regulation of phase-separated assemblies to be investigated and pivotal roles of protein posttranslational modifications to be demonstrated. By surveying the subcellular local...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329168/ https://www.ncbi.nlm.nih.gov/pubmed/33731873 http://dx.doi.org/10.1038/s41418-021-00763-6 |