USP42 drives nuclear speckle mRNA splicing via directing dynamic phase separation to promote tumorigenesis

Liquid–liquid phase separation is considered a generic approach to organize membrane-less compartments, enabling the dynamic regulation of phase-separated assemblies to be investigated and pivotal roles of protein posttranslational modifications to be demonstrated. By surveying the subcellular local...

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Detalles Bibliográficos
Autores principales: Liu, Shuyan, Wang, Taishu, Shi, Yulin, Bai, Lu, Wang, Shanshan, Guo, Dong, Zhang, Yang, Qi, Yangfan, Chen, Chaoqun, Zhang, Jinrui, Zhang, Yingqiu, Liu, Quentin, Yang, Qingkai, Wang, Yang, Liu, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329168/
https://www.ncbi.nlm.nih.gov/pubmed/33731873
http://dx.doi.org/10.1038/s41418-021-00763-6

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