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The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity

Dendritic cell (DC) development is orchestrated by lineage-determining transcription factors (TFs). Although, members of the activator-protein-1 (AP-1) family, including Batf3, have been implicated in conventional (c)DC specification, the role of Jun proteins is poorly understood. Here, we identifie...

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Detalles Bibliográficos
Autores principales: Novoszel, Philipp, Drobits, Barbara, Holcmann, Martin, Fernandes, Cristiano De Sa, Tschismarov, Roland, Derdak, Sophia, Decker, Thomas, Wagner, Erwin F., Sibilia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329169/
https://www.ncbi.nlm.nih.gov/pubmed/33758366
http://dx.doi.org/10.1038/s41418-021-00765-4