The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene

Inflammation increases the risk of cardiometabolic disease. Delineating specific inflammatory pathways and biomarkers of their activity could identify the mechanistic underpinnings of the increased risk. Plasma levels of kynurenine, a metabolite involved in inflammation, associates with cardiometabo...

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Detalles Bibliográficos
Autores principales: Bagheri, Minoo, Wang, Chuan, Shi, Mingjian, Manouchehri, Ali, Murray, Katherine T., Murphy, Matthew B., Shaffer, Christian M., Singh, Kritika, Davis, Lea K., Jarvik, Gail P., Stanaway, Ian B., Hebbring, Scott, Reilly, Muredach P., Gerszten, Robert E., Wang, Thomas J., Mosley, Jonathan D., Ferguson, Jane F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329184/
https://www.ncbi.nlm.nih.gov/pubmed/34341450
http://dx.doi.org/10.1038/s41598-021-95154-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329184/
https://www.ncbi.nlm.nih.gov/pubmed/34341450
http://dx.doi.org/10.1038/s41598-021-95154-9

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