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The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene
Inflammation increases the risk of cardiometabolic disease. Delineating specific inflammatory pathways and biomarkers of their activity could identify the mechanistic underpinnings of the increased risk. Plasma levels of kynurenine, a metabolite involved in inflammation, associates with cardiometabo...
Autores principales: | Bagheri, Minoo, Wang, Chuan, Shi, Mingjian, Manouchehri, Ali, Murray, Katherine T., Murphy, Matthew B., Shaffer, Christian M., Singh, Kritika, Davis, Lea K., Jarvik, Gail P., Stanaway, Ian B., Hebbring, Scott, Reilly, Muredach P., Gerszten, Robert E., Wang, Thomas J., Mosley, Jonathan D., Ferguson, Jane F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329184/ https://www.ncbi.nlm.nih.gov/pubmed/34341450 http://dx.doi.org/10.1038/s41598-021-95154-9 |
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