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Increased renal function decline in fast metabolizers using extended-release tacrolimus after kidney transplantation

Fast metabolism of immediate-release tacrolimus (IR-Tac) is associated with decreased kidney function after renal transplantation (RTx) compared to slow metabolizers. We hypothesized, by analogy, that fast metabolism of extended-release tacrolimus (ER-Tac) is associated with worse renal function. We...

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Detalles Bibliográficos
Autores principales: Thölking, Gerold, Filensky, Brigitte, Jehn, Ulrich, Schütte-Nütgen, Katharina, Koch, Raphael, Kurschat, Christine, Pavenstädt, Hermann, Suwelack, Barbara, Reuter, Stefan, Kuypers, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329201/
https://www.ncbi.nlm.nih.gov/pubmed/34341448
http://dx.doi.org/10.1038/s41598-021-95201-5