The noncoding RNAs SNORD50A and SNORD50B-mediated TRIM21-GMPS interaction promotes the growth of p53 wild-type breast cancers by degrading p53

Small nucleolar RNA SNORD50A and SNORD50B (SNORD50A/B) has been reported to be recurrently deleted and function as a putative tumor suppressor in different types of cancer by binding to and suppressing the activity of the KRAS oncoproteins. Its deletion correlates with poorer patient survival. Howev...

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Detalles Bibliográficos
Autores principales: Su, Xi, Feng, Chao, Wang, Simeng, Shi, Liang, Gu, Qingqing, Zhang, Haihong, Lan, Xinhui, Zhao, Yuelei, Qiang, Wei, Ji, Meiju, Hou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329294/
https://www.ncbi.nlm.nih.gov/pubmed/33742136
http://dx.doi.org/10.1038/s41418-021-00762-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329294/
https://www.ncbi.nlm.nih.gov/pubmed/33742136
http://dx.doi.org/10.1038/s41418-021-00762-7

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