The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson’s disease

The pathogenesis of Parkinson’s disease (PD) remains unclear, and there is no disease-modifying agent for PD. Withaferin A (WA), a naturally occurring compound, has emerged as a neuroprotective agent. However, the mechanisms by which WA is neuroprotective in PD are unknown. Here we show that WA prot...

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Detalles Bibliográficos
Autores principales: Zhao, Miao, Wang, Bingwei, Zhang, Chenyu, Su, Zhijie, Guo, Bingbing, Zhao, Yun, Zheng, Ruimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329302/
https://www.ncbi.nlm.nih.gov/pubmed/33762743
http://dx.doi.org/10.1038/s41418-021-00767-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329302/
https://www.ncbi.nlm.nih.gov/pubmed/33762743
http://dx.doi.org/10.1038/s41418-021-00767-2

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