Integrated 3D-QSAR, molecular docking, and molecular dynamics simulation studies on 1,2,3-triazole based derivatives for designing new acetylcholinesterase inhibitors

Alzheimer’s disease (AD) is a multifactorial and polygenic disease. It is the most prevalent reason for dementia in the aging population. A dataset of twenty-six 1,2,3-triazole-based derivatives previously synthetized and evaluated for acetylcholinesterase inhibitory activity were subjected to the t...

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Detalles Bibliográficos
Autores principales: EL KHATABI, Khalil, AANOUZ, Ilham, El-MERNISSI, Reda, SINGH, Atul Kumar, AJANA, Mohammed Aziz, LAKHLIFI, Tahar, KUMAR, Shashank, BOUACHRINE, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329344/
https://www.ncbi.nlm.nih.gov/pubmed/34385858
http://dx.doi.org/10.3906/kim-2010-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329344/
https://www.ncbi.nlm.nih.gov/pubmed/34385858
http://dx.doi.org/10.3906/kim-2010-34

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