Case Report: Predicting the Range of Lamotrigine Concentration Using Pharmacokinetic Models Based on Monte Carlo Simulation: A Case Study of Antiepileptic Drug-Related Leukopenia

Lamotrigine (LTG), a wide-spectrum antiepileptic drug, is frequently associated with cutaneous side-effects, whereas hematological side-effects such as leukopenia have rarely been reported for it. We report the case of a 15-year-old Chinese female epileptic patient weighing 60 kg who developed combi...

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Detalles Bibliográficos
Autores principales: Zhu, Xiuqing, Xiao, Tao, Huang, Shanqing, Liu, Shujing, Li, Xiaolin, Shang, Dewei, Wen, Yuguan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329375/
https://www.ncbi.nlm.nih.gov/pubmed/34354594
http://dx.doi.org/10.3389/fphar.2021.706329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329375/
https://www.ncbi.nlm.nih.gov/pubmed/34354594
http://dx.doi.org/10.3389/fphar.2021.706329

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