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Case Report: Predicting the Range of Lamotrigine Concentration Using Pharmacokinetic Models Based on Monte Carlo Simulation: A Case Study of Antiepileptic Drug-Related Leukopenia
Lamotrigine (LTG), a wide-spectrum antiepileptic drug, is frequently associated with cutaneous side-effects, whereas hematological side-effects such as leukopenia have rarely been reported for it. We report the case of a 15-year-old Chinese female epileptic patient weighing 60 kg who developed combi...
Autores principales: | Zhu, Xiuqing, Xiao, Tao, Huang, Shanqing, Liu, Shujing, Li, Xiaolin, Shang, Dewei, Wen, Yuguan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329375/ https://www.ncbi.nlm.nih.gov/pubmed/34354594 http://dx.doi.org/10.3389/fphar.2021.706329 |
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