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Acquisition of a Stable and Transferable bla (NDM-5)-Positive Plasmid With Low Fitness Cost Leading to Ceftazidime/Avibactam Resistance in KPC-2-Producing Klebsiella pneumoniae During Treatment

The emergence and prevalence of carbapenem-resistant Enterobacteriaceae (CRE) have drawn worldwide attention. Ceftazidime/avibactam (CAZ/AVI) gives us a valuable alternative strategy to treat CRE infections. Unfortunately, CAZ/AVI resistance could occur during CAZ/AVI treatment. The CAZ/AVI-resistan...

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Detalles Bibliográficos
Autores principales: Huang, Jiangqing, Zhang, Shengcen, Zhao, Zhichang, Chen, Min, Cao, Yingping, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329419/
https://www.ncbi.nlm.nih.gov/pubmed/34354959
http://dx.doi.org/10.3389/fcimb.2021.658070