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MiR-421 Binds to PINK1 and Enhances Neural Stem Cell Self-Renewal via HDAC3-Dependent FOXO3 Activation

Dysfunctions of neural stem cells (NSCs) often lead to a variety of neurological diseases. Thus, therapies based on NSCs have gained increasing attention recently. It has been documented that microRNA (miR)-421 represses the autophagy and apoptosis of mouse hippocampal neurons and confers a role in...

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Detalles Bibliográficos
Autores principales: Jia, Jiaoying, Wang, Ming, Liu, Min, Tan, Zhigang, Cui, Yan, Yu, Mengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329493/
https://www.ncbi.nlm.nih.gov/pubmed/34354990
http://dx.doi.org/10.3389/fcell.2021.621187