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Combining SARS-CoV-2 Proofreading Exonuclease and RNA-Dependent RNA Polymerase Inhibitors as a Strategy to Combat COVID-19: A High-Throughput in silico Screening

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people worldwide. Currently, many clinical trials in search of effective COVID-19 drugs are underway. Viral RNA-dependent RNA polymerase (RdRp) remains the target of choice for prophylactic or curative treatment of...

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Detalles Bibliográficos
Autores principales: Khater, Shradha, Kumar, Pawan, Dasgupta, Nandini, Das, Gautam, Ray, Shashikant, Prakash, Amresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329495/
https://www.ncbi.nlm.nih.gov/pubmed/34354677
http://dx.doi.org/10.3389/fmicb.2021.647693