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Machine learning reveals sequence-function relationships in family 7 glycoside hydrolases

Family 7 glycoside hydrolases (GH7) are among the principal enzymes for cellulose degradation in nature and industrially. These enzymes are often bimodular, including a catalytic domain and carbohydrate-binding module (CBM) attached via a flexible linker, and exhibit an active site that binds cello-...

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Detalles Bibliográficos
Autores principales: Gado, Japheth E., Harrison, Brent E., Sandgren, Mats, Ståhlberg, Jerry, Beckham, Gregg T., Payne, Christina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329511/
https://www.ncbi.nlm.nih.gov/pubmed/34216620
http://dx.doi.org/10.1016/j.jbc.2021.100931