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Inhibition of Lipoxygenases Showed No Benefit for the Musculoskeletal System in Estrogen Deficient Rats

BACKGROUND: In previous studies, we reported the beneficial impact of two lipoxygenase-inhibitors, Baicalein and Zileuton, on osteoporotic bone in a postmenopausal rat model. Whereas subcutaneous Baicalein predominantly improved cortical bone, Zileuton enhanced vertebral and femoral trabecular bone....

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Detalles Bibliográficos
Autores principales: Saul, Dominik, Hohl, Friederike Eva, Franz, Max Konrad, Meyer, Ilka, Taudien, Stefan, Roch, Paul Jonathan, Sehmisch, Stephan, Komrakova, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329538/
https://www.ncbi.nlm.nih.gov/pubmed/34354672
http://dx.doi.org/10.3389/fendo.2021.706504