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Serum extracellular vesicles containing MIAT induces atrial fibrosis, inflammation and oxidative stress to promote atrial remodeling and atrial fibrillation via blockade of miR‐485‐5p‐mediated CXCL10 inhibition

BACKGROUND: Atrial fibrillation (AF), a supraventricular arrhythmia that impairs cardiac function, is a main source of morbidity and mortality. Serum‐derived extracellular vesicles (EVs) have been identified to carry potential biomarker or target for the diagnosis and treatment of AF. We intended to...

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Detalles Bibliográficos
Autores principales: Chen, Yingwei, Chen, Xiaojie, Li, Haiyu, Li, Yunpeng, Cheng, Dong, Tang, Yi, Sang, Haiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329545/
https://www.ncbi.nlm.nih.gov/pubmed/34459123
http://dx.doi.org/10.1002/ctm2.482