DNA Polymerase Iota Promotes Esophageal Squamous Cell Carcinoma Proliferation Through Erk-OGT-Induced G6PD Overactivation

Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers with rapid progression and a high mortality rate. Our previous study demonstrated that DNA polymerase iota (Pol ι) is overexpressed in ESCC tumors and correlates with poor prognosis. However, its role in ESCC proliferation r...

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Detalles Bibliográficos
Autores principales: Su, Zhenzi, Gao, Aidi, Li, Xiaoqing, Zou, Shitao, He, Chao, Wu, Jinchang, Ding, Wei-Qun, Zhou, Jundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329663/
https://www.ncbi.nlm.nih.gov/pubmed/34354953
http://dx.doi.org/10.3389/fonc.2021.706337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329663/
https://www.ncbi.nlm.nih.gov/pubmed/34354953
http://dx.doi.org/10.3389/fonc.2021.706337

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