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Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia–Reperfusion With Increased Blood–Brain Barrier Disruption

It has been reported that the mechanistic target of rapamycin (mTOR) pathway is involved in cerebral ischemia–reperfusion injury. One of the important pathological changes during reperfusion after cerebral ischemia is disruption of blood–brain barrier (BBB). Rapamycin, a first-generation mTOR inhibi...

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Detalles Bibliográficos
Autores principales: Chi, Oak Z., Liu, Xia, Cofano, Sean, Patel, Nikhil, Jacinto, Estela, Weiss, Harvey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329705/
https://www.ncbi.nlm.nih.gov/pubmed/34354602
http://dx.doi.org/10.3389/fphys.2021.706528