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Fenofibrate inhibits TGF‐β‐induced myofibroblast differentiation and activation in human lung fibroblasts in vitro

Fenofibrate (FF), a peroxisome proliferator‐activated receptor‐alpha (PPAR‐α) agonist and a lipid‐lowering agent, can decrease experimental pulmonary fibrosis. However, the mechanisms underlying the antifibrotic effect of FF remain unknown. Hence, this study was conducted to evaluate the effects of...

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Detalles Bibliográficos
Autores principales: Kikuchi, Ryota, Maeda, Yuki, Tsuji, Takao, Yamaguchi, Kazuhiro, Abe, Shinji, Nakamura, Hiroyuki, Aoshiba, Kazutetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329776/
https://www.ncbi.nlm.nih.gov/pubmed/34228906
http://dx.doi.org/10.1002/2211-5463.13247