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Fenofibrate inhibits TGF‐β‐induced myofibroblast differentiation and activation in human lung fibroblasts in vitro
Fenofibrate (FF), a peroxisome proliferator‐activated receptor‐alpha (PPAR‐α) agonist and a lipid‐lowering agent, can decrease experimental pulmonary fibrosis. However, the mechanisms underlying the antifibrotic effect of FF remain unknown. Hence, this study was conducted to evaluate the effects of...
Autores principales: | Kikuchi, Ryota, Maeda, Yuki, Tsuji, Takao, Yamaguchi, Kazuhiro, Abe, Shinji, Nakamura, Hiroyuki, Aoshiba, Kazutetsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329776/ https://www.ncbi.nlm.nih.gov/pubmed/34228906 http://dx.doi.org/10.1002/2211-5463.13247 |
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