Cargando…

Lipoxin A4 protects primary spinal cord neurons from Erastin‐induced ferroptosis by activating the Akt/Nrf2/HO‐1 signaling pathway

Ferroptosis is an iron‐dependent programmed cell death, which participates in the pathogenesis of spinal cord injury (SCI). Our previous study has revealed that Lipoxin A4 (LXA4) exerts a protective role in SCI. Here, we investigated whether LXA4 can protect SCI through inhibiting neuronal ferroptos...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Na, Lu, Tan, Yang, Libin, Dong, Yonghan, Liu, Xiaotan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329788/
https://www.ncbi.nlm.nih.gov/pubmed/34048148
http://dx.doi.org/10.1002/2211-5463.13203