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Protein structure prediction by AlphaFold2: are attention and symmetries all you need?

The functions of most proteins result from their 3D structures, but determining their structures experimentally remains a challenge, despite steady advances in crystallography, NMR and single-particle cryoEM. Computationally predicting the structure of a protein from its primary sequence has long be...

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Detalles Bibliográficos
Autores principales: Bouatta, Nazim, Sorger, Peter, AlQuraishi, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329862/
https://www.ncbi.nlm.nih.gov/pubmed/34342271
http://dx.doi.org/10.1107/S2059798321007531