Knockdown of DNA methyltransferase 1 reduces DNA methylation and alters expression patterns of cardiac genes in embryonic cardiomyocytes

We previously found that DNA methyltransferase 3a (DNMT3a) plays an important role in regulating embryonic cardiomyocyte gene expression, morphology, and function. In this study, we investigated the role of the most abundant DNMT in mammalian cells, DNMT1, in these processes. It is known that DNMT1...

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Detalles Bibliográficos
Autores principales: Fang, Xiefan, Poulsen, Ryan, Zhao, Lu, Wang, Jingjing, Rivkees, Scott A., Wendler, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329956/
https://www.ncbi.nlm.nih.gov/pubmed/34235895
http://dx.doi.org/10.1002/2211-5463.13252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329956/
https://www.ncbi.nlm.nih.gov/pubmed/34235895
http://dx.doi.org/10.1002/2211-5463.13252

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