INHIBITION OF TOLL-LIKE RECEPTOR 4 PROTECTS AGAINST INFLAMMATION-INDUCED MECHANOBIOLOGICAL ALTERATIONS TO INTERVERTEBRAL DISC CELLS

Intervertebral disc (IVD) degeneration is associated with elevated levels of inflammatory cytokines implicated in disease aetiology and matrix degradation. Toll-like receptor-4 (TLR4) has been shown to participate in the inflammatory responses of the nucleus pulposus (NP) and its levels are upregula...

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Detalles Bibliográficos
Autores principales: Jacobsen, T.D., Hernandez, P.A., Chahine, N.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329983/
https://www.ncbi.nlm.nih.gov/pubmed/34013512
http://dx.doi.org/10.22203/eCM.v041a37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329983/
https://www.ncbi.nlm.nih.gov/pubmed/34013512
http://dx.doi.org/10.22203/eCM.v041a37

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