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Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell loss

BACKGROUND: Loss of pancreatic insulin-secreting β-cells due to metabolic or autoimmune damage leads to the development of diabetes. The discovery that α-cells can be efficiently reprogrammed into insulin-secreting cells in mice and humans has opened promising avenues for innovative diabetes therapi...

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Detalles Bibliográficos
Autores principales:	Oropeza, Daniel, Cigliola, Valentina, Romero, Agustín, Chera, Simona, Rodríguez-Seguí, Santiago A., Herrera, Pedro L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330016/ https://www.ncbi.nlm.nih.gov/pubmed/34340653 http://dx.doi.org/10.1186/s12864-021-07812-x

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