Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland

BACKGROUND: The ovarian hormones estrogen and progesterone (EP) are implicated in breast cancer causation. A specific consequence of progesterone exposure is the expansion of the mammary stem cell (MSC) and luminal progenitor (LP) compartments. We hypothesized that this effect, and its molecular fac...

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Detalles Bibliográficos
Autores principales: Ranjan, Manish, Lee, Oukseub, Cottone, Gannon, Mirzaei Mehrabad, Elnaz, Spike, Benjamin T., Zeng, Zexian, Yadav, Shivangi, Chatterton, Robert, Kim, J. Julie, Clare, Susan E., Khan, Seema A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330021/
https://www.ncbi.nlm.nih.gov/pubmed/34344445
http://dx.doi.org/10.1186/s13058-021-01455-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330021/
https://www.ncbi.nlm.nih.gov/pubmed/34344445
http://dx.doi.org/10.1186/s13058-021-01455-2

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