Engineered hypoxia-responding Escherichia coli carrying cardiac peptide genes, suppresses tumor growth, angiogenesis and metastasis in vivo

Development of engineered non-pathogenic bacteria, capable of expressing anti-cancer proteins under tumor-specific conditions, is an ideal approach for selectively eradicating proliferating cancer cells. Herein, using an engineered hypoxia responding nirB promoter, we developed an engineered Escheri...

Descripción completa

Detalles Bibliográficos
Autores principales: Samadi, Mitra, Majidzadeh-A, Keivan, Salehi, Malihe, Jalili, Neda, Noorinejad, Zeinab, Mosayebzadeh, Marjan, Muhammadnejad, Ahad, Sharif khatibi, Azadeh, Moradi-Kalbolandi, Shima, Farahmand, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330025/
https://www.ncbi.nlm.nih.gov/pubmed/34344421
http://dx.doi.org/10.1186/s13036-021-00269-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330025/
https://www.ncbi.nlm.nih.gov/pubmed/34344421
http://dx.doi.org/10.1186/s13036-021-00269-2

Ejemplares similares