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Engineered hypoxia-responding Escherichia coli carrying cardiac peptide genes, suppresses tumor growth, angiogenesis and metastasis in vivo

Development of engineered non-pathogenic bacteria, capable of expressing anti-cancer proteins under tumor-specific conditions, is an ideal approach for selectively eradicating proliferating cancer cells. Herein, using an engineered hypoxia responding nirB promoter, we developed an engineered Escheri...

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Detalles Bibliográficos
Autores principales:	Samadi, Mitra, Majidzadeh-A, Keivan, Salehi, Malihe, Jalili, Neda, Noorinejad, Zeinab, Mosayebzadeh, Marjan, Muhammadnejad, Ahad, Sharif khatibi, Azadeh, Moradi-Kalbolandi, Shima, Farahmand, Leila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330025/ https://www.ncbi.nlm.nih.gov/pubmed/34344421 http://dx.doi.org/10.1186/s13036-021-00269-2

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