Systematic assessment of gene co-regulation within chromatin domains determines differentially active domains across human cancers

BACKGROUND: Spatial interactions and insulation of chromatin regions are associated with transcriptional regulation. Domains of frequent chromatin contacts are proposed as functional units, favoring and delimiting gene regulatory interactions. However, contrasting evidence supports the association b...

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Detalles Bibliográficos
Autores principales: Zufferey, Marie, Liu, Yuanlong, Tavernari, Daniele, Mina, Marco, Ciriello, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330107/
https://www.ncbi.nlm.nih.gov/pubmed/34344431
http://dx.doi.org/10.1186/s13059-021-02436-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330107/
https://www.ncbi.nlm.nih.gov/pubmed/34344431
http://dx.doi.org/10.1186/s13059-021-02436-6

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