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Systematic assessment of gene co-regulation within chromatin domains determines differentially active domains across human cancers
BACKGROUND: Spatial interactions and insulation of chromatin regions are associated with transcriptional regulation. Domains of frequent chromatin contacts are proposed as functional units, favoring and delimiting gene regulatory interactions. However, contrasting evidence supports the association b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330107/ https://www.ncbi.nlm.nih.gov/pubmed/34344431 http://dx.doi.org/10.1186/s13059-021-02436-6 |