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Complement C3a activates osteoclasts by regulating the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma

OBJECTIVE: Myeloma bone disease (MBD) is the most common complication of multiple myeloma (MM). Our previous study showed that the serum levels of C3/C4 in MM patients were significantly positively correlated with the severity of bone disease. However, the mechanism of C3a/C4a in osteoclasts MM pati...

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Detalles Bibliográficos
Autores principales: Jiang, Fengjuan, Liu, Hui, Peng, Fengping, Liu, Zhaoyun, Ding, Kai, Song, Jia, Li, Lijuan, Chen, Jin, Shao, Qing, Yan, Siyang, De Veirman, Kim, Vanderkerken, Karin, Fu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330530/
https://www.ncbi.nlm.nih.gov/pubmed/33960177
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0430