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Complement C3a activates osteoclasts by regulating the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma
OBJECTIVE: Myeloma bone disease (MBD) is the most common complication of multiple myeloma (MM). Our previous study showed that the serum levels of C3/C4 in MM patients were significantly positively correlated with the severity of bone disease. However, the mechanism of C3a/C4a in osteoclasts MM pati...
Autores principales: | Jiang, Fengjuan, Liu, Hui, Peng, Fengping, Liu, Zhaoyun, Ding, Kai, Song, Jia, Li, Lijuan, Chen, Jin, Shao, Qing, Yan, Siyang, De Veirman, Kim, Vanderkerken, Karin, Fu, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Compuscript
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330530/ https://www.ncbi.nlm.nih.gov/pubmed/33960177 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0430 |
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