Anticoagulation therapy promotes the tumor immune-microenvironment and potentiates the efficacy of immunotherapy by alleviating hypoxia

PURPOSE: Here, this study verifies that cancer-associated thrombosis (CAT) accelerates hypoxia, which is detrimental to the tumor immune microenvironment by limiting tumor perfusion. Therefore, we designed an oral anticoagulant therapy to improve the immunosuppressive tumor microenvironment and pote...

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Detalles Bibliográficos
Autores principales: Choi, Jeong Uk, Lee, Na Kyeong, Seo, Hyungseok, Chung, Seung Woo, Al-Hilal, Taslim A, Park, Seong Jin, Kweon, Seho, Min, Nuri, Kim, Sang Kyoon, Ahn, Seohyun, Kim, Uk-Il, Park, Jin Woo, Kang, Chang-Yuil, Kim, In-San, Kim, Sang Yoon, Kim, Kyungjin, Byun, Youngro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330593/
https://www.ncbi.nlm.nih.gov/pubmed/34341129
http://dx.doi.org/10.1136/jitc-2021-002332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330593/
https://www.ncbi.nlm.nih.gov/pubmed/34341129
http://dx.doi.org/10.1136/jitc-2021-002332

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