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Effect of XlogP and hansen solubility parameters on the prediction of small molecule modified docetaxel, doxorubicin and irinotecan conjugates forming stable nanoparticles

Small molecule-chemotherapeutic drug conjugate nanoparticles (SMCDC NPs) has a great advantage in improving drug loading. However, the factors which influence these conjugates forming stable nanoparticles (NPs) are currently unclear. In our previous studies, we synthesized a series of fatty acid-pac...

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Detalles Bibliográficos
Autores principales: Xu, Mei-Qi, Zhong, Ting, Yao, Xin, Li, Zhuo-Yue, Li, Hui, Wang, Jing-Ru, Feng, Zhen-Han, Zhang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330778/
https://www.ncbi.nlm.nih.gov/pubmed/34319209
http://dx.doi.org/10.1080/10717544.2021.1958107