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Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1

Superoxide Dismutase 1 (SOD1) is an antioxidant enzyme that protects the cells from radical oxygen species. To study the behavior of endogenous SOD1 under a microscope, we genetically modified H1 human embryonic stem cells (hESCs) to express SOD1 fused with a SNAP-tag, a protein tag that can be cova...

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Detalles Bibliográficos
Autores principales: Huang, Pei-San, Wen, Meng-Hsuan, Xie, Xihong, Xu, An, Lee, Dung-Fang, Chen, Tai-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330834/
https://www.ncbi.nlm.nih.gov/pubmed/34118566
http://dx.doi.org/10.1016/j.scr.2021.102415