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Highly conserved and cis-acting lncRNAs produced from paralogous regions in the center of HOXA and HOXB clusters in the endoderm lineage

Long noncoding RNAs (lncRNAs) have been shown to play important roles in gene regulatory networks acting in early development. There has been rapid turnover of lncRNA loci during vertebrate evolution, with few human lncRNAs conserved beyond mammals. The sequences of these rare deeply conserved lncRN...

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Detalles Bibliográficos
Autores principales: Degani, Neta, Lubelsky, Yoav, Perry, Rotem Ben-Tov, Ainbinder, Elena, Ulitsky, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330917/
https://www.ncbi.nlm.nih.gov/pubmed/34280202
http://dx.doi.org/10.1371/journal.pgen.1009681