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Distributed hybrid-indexing of compressed pan-genomes for scalable and fast sequence alignment

Computational pan-genomics utilizes information from multiple individual genomes in large-scale comparative analysis. Genetic variation between case-controls, ethnic groups, or species can be discovered thoroughly using pan-genomes of such subpopulations. Whole-genome sequencing (WGS) data volumes a...

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Detalles Bibliográficos
Autores principales: Maarala, Altti Ilari, Arasalo, Ossi, Valenzuela, Daniel, Mäkinen, Veli, Heljanko, Keijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330939/
https://www.ncbi.nlm.nih.gov/pubmed/34343181
http://dx.doi.org/10.1371/journal.pone.0255260