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Distributed hybrid-indexing of compressed pan-genomes for scalable and fast sequence alignment
Computational pan-genomics utilizes information from multiple individual genomes in large-scale comparative analysis. Genetic variation between case-controls, ethnic groups, or species can be discovered thoroughly using pan-genomes of such subpopulations. Whole-genome sequencing (WGS) data volumes a...
Autores principales: | Maarala, Altti Ilari, Arasalo, Ossi, Valenzuela, Daniel, Mäkinen, Veli, Heljanko, Keijo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330939/ https://www.ncbi.nlm.nih.gov/pubmed/34343181 http://dx.doi.org/10.1371/journal.pone.0255260 |
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