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ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements

Transcription factors (TFs) often function as a module including both master factors and mediators binding at cis-regulatory regions to modulate nearby gene transcription. ChIP-seq profiling of multiple TFs makes it feasible to infer functional TF modules. However, when inferring TF modules based on...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Neuwald, Andrew F., Hilakivi-Clarke, Leena, Clarke, Robert, Xuan, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330942/
https://www.ncbi.nlm.nih.gov/pubmed/34292930
http://dx.doi.org/10.1371/journal.pcbi.1009203