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From structure to ætiology: a new window on the biology of leucine-rich repeat kinase 2 and Parkinson's disease
Since the discovery of mutations in leucine-rich repeat kinase 2 (LRRK2) as an underlying genetic cause for the development of Parkinson's disease (PD) in 2004 (Neuron 44, 601–607; Neuron 44, 595–600), and subsequent efforts to develop LRRK2 kinase inhibitors as a therapy for Parkinson's (...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Portland Press Ltd.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331089/ https://www.ncbi.nlm.nih.gov/pubmed/34328508 http://dx.doi.org/10.1042/BCJ20210383 |