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TWAS results are complementary to and less affected by linkage disequilibrium than GWAS
A genome-wide association study (GWAS) is used to identify genetic markers associated with phenotypic variation. In contrast, a transcriptome-wide association study (TWAS) detects associations between gene expression levels and phenotypic variation. It has previously been shown that in the cross-pol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331151/ https://www.ncbi.nlm.nih.gov/pubmed/33823025 http://dx.doi.org/10.1093/plphys/kiab161 |