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TWAS results are complementary to and less affected by linkage disequilibrium than GWAS

A genome-wide association study (GWAS) is used to identify genetic markers associated with phenotypic variation. In contrast, a transcriptome-wide association study (TWAS) detects associations between gene expression levels and phenotypic variation. It has previously been shown that in the cross-pol...

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Detalles Bibliográficos
Autores principales: Li, Delin, Liu, Qiang, Schnable, Patrick S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331151/
https://www.ncbi.nlm.nih.gov/pubmed/33823025
http://dx.doi.org/10.1093/plphys/kiab161