AAV ablates neurogenesis in the adult murine hippocampus

Recombinant adeno-associated virus (rAAV) has been widely used as a viral vector across mammalian biology and has been shown to be safe and effective in human gene therapy. We demonstrate that neural progenitor cells (NPCs) and immature dentate granule cells (DGCs) within the adult murine hippocampu...

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Detalles Bibliográficos
Autores principales: Johnston, Stephen, Parylak, Sarah L, Kim, Stacy, Mac, Nolan, Lim, Christina, Gallina, Iryna, Bloyd, Cooper, Newberry, Alexander, Saavedra, Christian D, Novak, Ondrej, Gonçalves, J Tiago, Gage, Fred H, Shtrahman, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331179/
https://www.ncbi.nlm.nih.gov/pubmed/34259630
http://dx.doi.org/10.7554/eLife.59291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331179/
https://www.ncbi.nlm.nih.gov/pubmed/34259630
http://dx.doi.org/10.7554/eLife.59291

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