NICEdrug.ch, a workflow for rational drug design and systems-level analysis of drug metabolism

The discovery of a drug requires over a decade of intensive research and financial investments – and still has a high risk of failure. To reduce this burden, we developed the NICEdrug.ch resource, which incorporates 250,000 bioactive molecules, and studied their enzymatic metabolic targets, fate, an...

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Detalles Bibliográficos
Autores principales: MohammadiPeyhani, Homa, Chiappino-Pepe, Anush, Haddadi, Kiandokht, Hafner, Jasmin, Hadadi, Noushin, Hatzimanikatis, Vassily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331181/
https://www.ncbi.nlm.nih.gov/pubmed/34340747
http://dx.doi.org/10.7554/eLife.65543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331181/
https://www.ncbi.nlm.nih.gov/pubmed/34340747
http://dx.doi.org/10.7554/eLife.65543

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