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SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways

SOX2 expression levels are crucial for the balance between maintenance and differentiation of airway progenitor cells during development and regeneration. Here, we describe patterning of the mouse proximal airway epithelium by SOX21, which coincides with high levels of SOX2 during development. Airwa...

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Detalles Bibliográficos
Autores principales: Eenjes, Evelien, Buscop-van Kempen, Marjon, Boerema-de Munck, Anne, Edel, Gabriela G, Benthem, Floor, de Kreij-de Bruin, Lisette, Schnater, Marco, Tibboel, Dick, Collins, Jennifer, Rottier, Robbert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331192/
https://www.ncbi.nlm.nih.gov/pubmed/34286693
http://dx.doi.org/10.7554/eLife.57325