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A novel yeast-based high-throughput method for the identification of protein palmitoylation inhibitors

Protein S-acylation or palmitoylation is a widespread post-translational modification that consists of the addition of a lipid molecule to cysteine residues of proteins through a thioester bond. Palmitoylation and palmitoyltransferases (PATs) have been linked to several types of cancers, diseases of...

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Detalles Bibliográficos
Autores principales: Coronel Arrechea, Consuelo, Giolito, María Luz, García, Iris Alejandra, Soria, Gastón, Valdez Taubas, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331233/
https://www.ncbi.nlm.nih.gov/pubmed/34343464
http://dx.doi.org/10.1098/rsob.200415