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A novel yeast-based high-throughput method for the identification of protein palmitoylation inhibitors
Protein S-acylation or palmitoylation is a widespread post-translational modification that consists of the addition of a lipid molecule to cysteine residues of proteins through a thioester bond. Palmitoylation and palmitoyltransferases (PATs) have been linked to several types of cancers, diseases of...
Autores principales: | Coronel Arrechea, Consuelo, Giolito, María Luz, García, Iris Alejandra, Soria, Gastón, Valdez Taubas, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331233/ https://www.ncbi.nlm.nih.gov/pubmed/34343464 http://dx.doi.org/10.1098/rsob.200415 |
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